Recombinant Human CMPK1 Protein (His Tag)

Specifications

Catalog number

PKSH030319

Size / count

50 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis.

Synonyms

CK; CMK; CMPK; UMK; UMP-CMPK; UMPK

UniProt

P30085

Accession Number

P30085

Expression System

Baculovirus-Insect Cells

Tag

N-His

Sequence

Met 1-Gly 196

Field of Research

Epigenetics and nuclear signal; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

24.5 kDa

Observed Molecular Weight

27 kDa

Formulation

Supplied as sterile solution of 20mM Tris, 500mM Nacl, pH 7.4, 10% glycerol

Species

Human