Recombinant Human STK24/MST3 Protein (His Tag)

Specifications

Catalog number

PKSH030330

Size / count

50 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

MST3 encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants.

Synonyms

HEL-S-95; MST3; MST3B; RP11-111L24.5; STE20; STK3

UniProt

Q9Y6E0

Accession Number

Q9Y6E0-2

Expression System

Baculovirus-Insect Cells

Tag

N-His

Sequence

Met 1-His 431

Applications

Enzyme

Field of Research

Neuroscience, Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 82 % as determined by reducing SDS-PAGE.

Bioactivity

The specific activity was determined to be 62 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

50.3 kDa

Observed Molecular Weight

55 kDa

Formulation

Supplied as sterile solution of 50mM Tris, 100mM NaCl, pH 8.0, 20% glycerol, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT

Species

Human