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Product details

Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag)

Catalog number PKSH030359

Price for PKSH030359

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Size / count 50 µg

Specifications

Catalog number
PKSH030359
Size / count
50 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
DCAMKL1; also known as DCLK1; is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains; which bind microtubules and regulate microtubule polymerization; a C-terminal serine/threonine protein kinase domain; which shows substantial homology to Ca2+/calmodulin-dependent protein kinase; and a serine/proline-rich domain in between the doublecortin and the protein kinase domains; which mediates multiple protein-protein interactions. DCAMKL1 is involved in several different cellular processes; including neuronal migration; retrograde transport; neuronal apoptosis and neurogenesis. Its microtubule-polymerizing activity is independent of its protein kinase activity. DCAMKL1 may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. It may also participate in functions of the mature nervous system.
Synonyms
CL1; CLICK1; DCAMKL1; DCDC3A; DCLK
UniProt
O15075
Accession Number
O15075-1
Expression System
Baculovirus-Insect Cells
Tag
N-His-GST
Sequence
Met 1-Val 705
Applications
Enzyme
Field of Research
Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 84 % as determined by reducing SDS-PAGE.
Bioactivity
The specific activity was determined to be 6. 1 nmol/min/mg using synthetic Autocamtide-2 peptide (KKALRRQETVDAL-amide) as substrate.
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
106 kDa
Observed Molecular Weight
105 kDa
Formulation
Supplied as sterile solution of 20mM Tris, 500mM NaCl, pH 7.4, 10% glycerol, 0.5mM PMSF
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag)?

The catalog number for Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag) is PKSH030359.

What sizes are available for Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag)?

Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag) is available in the following size(s): 50 µg.

Is Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag) in stock?

Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag)?

Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag)?

Estimated delivery time for Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag)?

The safety data sheet for Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag) is available here: https://789.bio/eb/Ge1ivL.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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