Recombinant Human AKT2/PKB beta Protein (His & GST Tag)

Specifications

Catalog number

PKSH030382

Size / count

50 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

AKT2 (AKT Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with AKT2 include Hypoinsulinemic Hypoglycemia With Hemihypertrophy and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and RANK Signaling in Osteoclasts. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AKT1.

Synonyms

HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA

UniProt

P31751

Accession Number

NP_001617.1

Expression System

Baculovirus-Insect Cells

Tag

N-His-GST

Sequence

Met 1-Glu481

Field of Research

Signal Transduction; Cardiovascular; Neuroscience; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

83.6 kDa

Formulation

Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4

Species

Human