• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag)

Catalog number PKSH030414

Price for PKSH030414

Sign In for Pricing

Size / count 50 µg

Specifications

Catalog number
PKSH030414
Size / count
50 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and MAP kinase kinase subfamily. MAP2K6 / MKK6 contains one protein kinase domain. Mitogen-activated protein kinases are members of a conserved cascade of kinases involved in many signal transduction pathways. They stimulate phosphorylation of transcription factors in response to extracellular signals such as growth factors, cytokines, ultraviolet light, and stress-inducing agents. MAP2K6 / MKK6 exists in a variety of alternatively spliced isoforms with distinct patterns of tissue expression. Isoform 2 of MAP2K6 / MKK6 is only expressed in skeletal muscle. Isoform 1 of MAP2K6 / MKK6 is expressed in skeletal muscle, heart, and to a lesser extent in liver or pancreas.
Synonyms
MAP2K6 ; MAPKK6; MEK6; MKK6; PRKMK6; SAPKK-3; SAPKK3
UniProt
P52564
Accession Number
P52564-1
Expression System
Baculovirus-Insect Cells
Tag
N-His-GST
Sequence
Met 1-Asp 334; Ser 207/Asp; Thr 211/Asp
Applications
Enzyme
Field of Research
Cell Biology, Signal Transduction, Immunology, Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 88 % as determined by reducing SDS-PAGE.
Bioactivity
The specific activity was determined to be 1250 nmol/min/mg using inactive MAPK14 as substrate.
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
65.3 kDa
Observed Molecular Weight
60 kDa
Formulation
Supplied as sterile solution of 20mM Tris, 500mM NaCl, pH 8.0, 10% glycerol
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag)?

The catalog number for Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag) is PKSH030414.

What sizes are available for Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag)?

Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag) is available in the following size(s): 50 µg.

Is Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag) in stock?

Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag)?

Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag)?

Estimated delivery time for Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag)?

The safety data sheet for Recombinant Human MKK6 Protein (207 Ser/Asp, 211 Thr/Asp, His & GST Tag) is available here: https://789.bio/eb/q1Gu9S.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

You Might Also Like
CD8 (RIV11), CF555 conjugate, 0.1mg/mL
CD8 (RIV11), CF555 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC550333-500
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040994-100
CD5 (Cris-1), CF740 conjugate, 0.1mg/mL
CD5 (Cris-1), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740176-500
Cytokeratin 10 (KRT10/844), CF488A conjugate, 0.1mg/mL
Cytokeratin 10 (KRT10/844), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880844-500
Vimentin (VM1170), CF647 conjugate, 0.1mg/mL
Vimentin (VM1170), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471170-500
CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (rLPFS2/1611), CF405S conjugate, 0.1mg/mL
CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (rLPFS2/1611), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041976-500
MCM7 (Proliferation Marker) (MCM7/1468), CF568 conjugate, 0.1mg/mL
MCM7 (Proliferation Marker) (MCM7/1468), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC681468-500
Moesin (MSN/492), CF405S conjugate, 0.1mg/mL
Moesin (MSN/492), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040492-500