Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) — image 1 of 3

Product details

Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag)

Q: What is the catalog number for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag)?

The catalog number for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) is PKSH030420.

Q: What is the estimated delivery time for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag)?

Estimated delivery time for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag)?

The safety data sheet for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) is available here: https://789.bio/eb/v14mjD.

Q: What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Q: Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

Q: What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

Catalog number PKSH030420

Price for PKSH030420

Size / count 50 µg

Specifications

Catalog number: PKSH030420
Size / count: 50 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2, up-regulates matrix metallloproteinase 1 (MMP-1) and MMP-2 expression in cellular matrix. DDR2/CD167b was found to recognise the triple-helical region of collagen X as well as the NC1 domain. Binding to the collagenous region was dependent on the triple-helical conformation. DDR2/CD167b autophosphorylation was induced by the collagen X triple-helical region but not the NC1 domain, indicating that the triple-helical region of collagen X contains a specific DDR2 binding site that is capable of receptor activation. DDR2/CD167b is induced during stellate cell activation and implicate the phosphorylated receptor as a mediator of MMP-2 release and growth stimulation in response to type I collagen. Moreover, type I collagen-dependent upregulation of DDR2/CD167b expression establishes a positive feedback loop in activated stellate cells, leading to further proliferation and enhanced invasive activity.
Synonyms: CD167; MIG20a; NTRKR3; TKT; TYRO10
UniProt: Q16832
Accession Number: Q16832
Expression System: Baculovirus-Insect Cells
Tag: N-His-GST
Sequence: Arg422-Glu855
Applications: Enzyme
Field of Research: Cardiovascular; Neuroscience
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: The specific activity was determined to be 8 nmol/min/mg using synthetic AXLtide peptide (CKKSRGDYMTMQIG) as substrate.
Reconstitution: Not Applicable
Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight: 77.1 kDa
Observed Molecular Weight: 77 kDa
Formulation: Supplied as sterile solution of 20mM Tris, 500mM NaCl, pH 7.4, 10% glycerol
Species: Human

Frequently Asked Questions

What is the catalog number for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag)?

The catalog number for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) is PKSH030420.

What sizes are available for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag)?

Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) is available in the following size(s): 50 µg.

Is Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) in stock?

Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag)?

Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag)?

Estimated delivery time for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag)?

The safety data sheet for Recombinant Human DDR2 Kinase/CD167b Protein (aa 422-855, His & GST Tag) is available here: https://789.bio/eb/v14mjD.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.