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Product details

Recombinant Human PDGF-BB Protein (His Tag)

Catalog number PKSH030442-01

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Price for PKSH030442-01

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Size / count 50 µg

Specifications

Catalog number
PKSH030442-01
Size / count
50 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
Synonyms
Becaplermin; PDGF Subunit B; PDGF-2; PDGF2; PDGFB; Platelet-Derived Growth Factor B Chain; Platelet-Derived Growth Factor Beta Polypeptide; Platelet-Derived Growth Factor Subunit B; Proto-Oncogene c-Sis; SIS
UniProt
P01127
Accession Number
NP_148937.1
Expression System
Yeast
Tag
N-His
Sequence
Ser82-Thr190
Applications
ELISA
Field of Research
Signal Transduction; Cardiovascular; Cancer; Developmental Biology; metabolism
Endotoxin
Please contact us for more information.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Immobilized human PDGFB at 10μg/mL (100μL/well) can bind human PDGFRβ-Fch, the EC50 of human PDGFRβ-Fch is 0.05-0.2 μg/mL.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
14.3 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human PDGF-BB Protein (His Tag)?

The catalog number for Recombinant Human PDGF-BB Protein (His Tag) is PKSH030442.

What sizes are available for Recombinant Human PDGF-BB Protein (His Tag)?

Recombinant Human PDGF-BB Protein (His Tag) is available in the following size(s): 50 µg, 1 mg.

How many pack sizes does Recombinant Human PDGF-BB Protein (His Tag) come in?

Recombinant Human PDGF-BB Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human PDGF-BB Protein (His Tag) in stock?

Recombinant Human PDGF-BB Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human PDGF-BB Protein (His Tag)?

Recombinant Human PDGF-BB Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human PDGF-BB Protein (His Tag)?

Estimated delivery time for Recombinant Human PDGF-BB Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human PDGF-BB Protein (His Tag)?

The safety data sheet for Recombinant Human PDGF-BB Protein (His Tag) is available here: https://789.bio/eb/mPmrXT.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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