Recombinant Human GPD1/GDP-C Protein (E.coli, His Tag)

Specifications

Catalog number

PKSH030541

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

GPD1; also known as glycerolphosphate dehydrogenase 1; is a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. GPD1 catalyzes the reversible redox conversion ofdihydroxyacetone phosphate (DHAP) ; thus plays a critical role in carbohydrate and lipid metabolism. It also reduces nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. Meanwhile; GPD1 and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in GPD1 gene are a cause of transient infantile hypertriglyceridemia.

Synonyms

GPD-C; GPD1; GPDH-C; Glycerol-3-Phosphate Dehydrogenase [NAD (+) ] Cytoplasmic; HTGTI

UniProt

P21695

Accession Number

P21695

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Met349

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism

Endotoxin

Please contact us for more information.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

39.4 kDa

Observed Molecular Weight

33-37 kDa

Species

Human