Recombinant Human Annexin A8/ANXA8 Protein (His Tag)

Specifications

Catalog number

PKSH030551

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1), membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3) .MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4) .It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.

Synonyms

ANX8; ANXA8; Annexin A8; Annexin VIII; Annexin-8; VAC-Beta; Vascular Anticoagulant-Beta

UniProt

P13928

Accession Number

AAH73755.1

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Pro327

Field of Research

Cardiovascular, Signal Transduction

Endotoxin

Please contact us for more information.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

39.1 kDa

Observed Molecular Weight

35 kDa

Species

Human