Recombinant Human PSG6/PSG10 Protein (His Tag)

Specifications

Catalog number

PKSH030553

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

PSG6 is a pregnancy-specific glycoprotein (PSG) . PSGs are secreted proteins which are produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived from the placenta. Pregnancy specific glycoproteins (PSGs) are the most abundant placentally derived glycoproteins in the maternal serum. PSG1, PSG6, PSG6N, and PSG11 induce dose-dependent secretion of anti-inflammatory cytokines by human monocytes. Human and murine PSGs exhibit cross-species activity.

Synonyms

CGM3; PSBG-10; PSBG-12; PSBG-6; PSG10; PSG12; PSG6; PSGGB

UniProt

Q00889

Accession Number

NP_001027020

Expression System

Baculovirus-Insect Cells

Tag

C-His

Sequence

Met 1-His 424

Field of Research

Tags & Cell Markers

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 87 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

45.2 kDa

Observed Molecular Weight

58 kDa

Species

Human