Recombinant Human BPHL Protein (His Tag)

Specifications

Catalog number

PKSH030575

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. BPHL also activates valacyclovir to acyclovir. It may play a role in detoxification processes.

Synonyms

BPH-RP; MCNAA; VACVASE

UniProt

Q86WA6

Accession Number

Q86WA6-1

Expression System

E.coli

Tag

N-His

Sequence

Ser38-Gln291

Field of Research

Signal Transduction, Metabolism

Endotoxin

Please contact us for more information.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

30.7 kDa

Observed Molecular Weight

31 kDa

Species

Human