Recombinant Human BMF/Bcl2 modifying factor Protein (His Tag)

Specifications

Catalog number

PKSH030590

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

BMF (Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. BMF is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms

BMF

UniProt

Q96LC9

Accession Number

Q96LC9-1

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Arg184

Field of Research

Cell Biology, Signal Transduction

Endotoxin

Please contact us for more information.

Purity

> 85 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

22.3 kDa

Observed Molecular Weight

25 kDa

Species

Human