Recombinant Human DCBLD2/ESDN Protein (aa 1-482, His Tag)

Specifications

Catalog number

PKSH030592

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV (1) -related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor mediated signaling pathway, negative regulation of cell growth and so on.

Synonyms

CLCP1; CUB; CUB and LCCL domain-containing protein 2; DCBLD2; Discoidin; ESDN; Endothelial and smooth muscle cell-derived neuropilin-like protein; LCCL and coagulation factor V/VIII-homology domains protein 1

UniProt

Q96PD2

Accession Number

NP_563615.3

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-Ala482

Field of Research

Cardiovascular; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

52.6 kDa

Observed Molecular Weight

69-89 kDa

Species

Human