Recombinant Human CRELD1 Protein (His Tag)

Specifications

Catalog number

PKSH030636

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CRELD1 is a transmembrane glycoprotein. Epidermal growth factor (EGF) ­ like domain exists in CRELD1. EGF-like repeats are a class of cysteine-rich domains that mediate interactions between proteins of diverse function. EGF domains are found in proteins that are either completely secreted or have transmembrane regions that tether the protein to the cell surface. CRELD1 contains a 333 amino acid acid (aa) extracellular domain (ECD), two tandem transmembrane segments, and a second ECD of 15 aa. Defects in CRELD1 may cause susceptibility to atrioventricular septal defect type 2 which results in a persistent common atrioventricular canal.

Synonyms

AVSD2; CIRRIN

UniProt

Q96HD1

Accession Number

NP_001070883.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-Glu362

Field of Research

Cell biology; Cardiovascular

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

37.4 kDa

Observed Molecular Weight

51 kDa

Species

Human