Recombinant Human CLM-9/TREM4 Protein

Specifications

Catalog number

PKSH030648

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.

Synonyms

CD300 Antigen-Like Family Member G; CD300LG; CD300g; CLM-9; CLM9; CMRF35-Like Molecule 9; NEPMUCIN; TREM-4; TREM4; Triggering Receptor Expressed on Myeloid Cells 4

UniProt

Q6UXG3

Accession Number

AAH25395.1

Expression System

HEK293 Cells

Tag

None

Sequence

Met 1-Arg247

Field of Research

Immunology, Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

25.5 kDa

Observed Molecular Weight

61-66 kDa

Species

Human