Recombinant Human TLE3 Protein (aa 484-772, GST Tag)

Specifications

Catalog number

PKSH030727

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Immunoglobulin superfamily member 11 (IGSF11) are expressed on the plasma membrane in the tesis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to over expressed in colorectal cancers and hepatocellular carcinomas as well as intestinal-type gastric cancers compared to their corresponding non- cancerous tissues. The IGSF11 has also been found expressed abundantly in testis and ovary and the IGSF11 can be used as a candidate of cancer-testis antigen.

Synonyms

ESG; ESG3; GRG3; HsT18976

UniProt

Q04726

Accession Number

Q04726-1

Expression System

E.coli

Tag

N-GST

Sequence

Ser 484-Tyr 772

Field of Research

Signal Transduction, Epigenetics and Nuclear Signaling

Endotoxin

Please contact us for more information.

Purity

> 78 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

58.5 kDa

Observed Molecular Weight

58.5 kDa

Species

Human