Recombinant Human FKBP3/FKBP25 Protein (GST Tag)

Specifications

Catalog number

PKSH030809

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

BLBP; also known as FABP7; is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small; highly conserved; cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake; transport; and metabolism. BLBP is expressed; during development; in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition (PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives.

Synonyms

25 kDa FK506-binding protein;25 kDa FKBP; FK506-binding protein 3; FKBP-25; FKBP-3; FKBP25; Immunophilin FKBP25; PPIase FKBP3; Peptidyl-prolyl cis-trans isomerase FKBP3; Rapamycin-selective 25 kDa immunophilin; Rotamase

UniProt

Q00688

Accession Number

Q00688

Expression System

E.coli

Tag

N-GST

Sequence

Ala 2-Asp 224

Field of Research

Epigenetics and nuclear signal

Endotoxin

Please contact us for more information.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

52.0 kDa

Observed Molecular Weight

48 kDa

Species

Human