Recombinant Human FABP5 Protein

Specifications

Catalog number

PKSH030810

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fatty acid-binding protein; also known as Epidermal-type fatty acid-binding protein; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; E-FABP and FABP5; is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins (FABPs) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids; as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.

Synonyms

E-FABP; Epidermal-Type Fatty Acid-Binding Protein; FABP5; Fatty Acid-Binding Protein 5; Fatty Acid-Binding Protein Epidermal; PA-FABP; Psoriasis-Associated Fatty Acid-Binding Protein Homolog

UniProt

Q01469

Accession Number

Q01469

Expression System

E.coli

Tag

None

Sequence

Met 1-Glu 135

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism

Endotoxin

Please contact us for more information.

Purity

> 92 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

15.2 kDa

Species

Human