Recombinant Human NUDT2/Ap4A hydrolase Protein (His Tag)

Specifications

Catalog number

PKSH030819

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified.

Synonyms

APAH1

UniProt

P50583

Accession Number

P50583

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Ala 147

Field of Research

Epigenetics and nuclear signal

Endotoxin

Please contact us for more information.

Purity

> 97 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

18.3 kDa

Observed Molecular Weight

20 kDa

Species

Human