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Product details

Recombinant Human Cathepsin D/CTSD Protein (His Tag)

Catalog number PKSH030822-01

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Price for PKSH030822-01

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Size / count 50 µg

Specifications

Catalog number
PKSH030822-01
Size / count
50 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Cathepsin D (CTSD) ; a well known lysosomal aspartyl protease and belongs to the peptidase C1 family; which is a normal and major component of lysosomes; and is found in almost all cells and tissues of mammals. Its mostly described function is intracellular catabolism in lysosomal compartments; other physiological effect include hormone and antigen processing. Cathepsin D has a specificity similar to but narrower than that of pepsin A. Cathepsin D plays an important role in the degradation of proteins; the generation of bioactive proteins; antigen processing; etc. Among different role in cell physiology; a new function of this enzyme is examined. Cathepsin D is an important regulator of apoptotic pathways in cells. It acts at different stage of intrinsic and extrinsic pathway of apoptosis. In addition; CTSD secreted from human prostate carcinoma cells are responsible for the generation of angiostatin; a potent endogenous inhibitor of angiogenesis; suggesting its contribution to the prevention of tumor growth and angiogenesis-dependent growth of metastases.
Synonyms
CLN10; CPSD; CTSD; Cathepsin D; HEL-S-130P
UniProt
P07339
Accession Number
P07339
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Leu 412
Applications
ELISA
Field of Research
Signal Transduction; Cell biology; Neuroscience; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 97 % as determined by reducing SDS-PAGE.
Bioactivity
Measured by its ability to bind biotinylated human CTSS-His in a functional ELISA.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
44.0 kDa
Observed Molecular Weight
40-110 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Cathepsin D/CTSD Protein (His Tag)?

The catalog number for Recombinant Human Cathepsin D/CTSD Protein (His Tag) is PKSH030822.

What sizes are available for Recombinant Human Cathepsin D/CTSD Protein (His Tag)?

Recombinant Human Cathepsin D/CTSD Protein (His Tag) is available in the following size(s): 50 µg, 1 mg.

How many pack sizes does Recombinant Human Cathepsin D/CTSD Protein (His Tag) come in?

Recombinant Human Cathepsin D/CTSD Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human Cathepsin D/CTSD Protein (His Tag) in stock?

Recombinant Human Cathepsin D/CTSD Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Cathepsin D/CTSD Protein (His Tag)?

Recombinant Human Cathepsin D/CTSD Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Cathepsin D/CTSD Protein (His Tag)?

Estimated delivery time for Recombinant Human Cathepsin D/CTSD Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Cathepsin D/CTSD Protein (His Tag)?

The safety data sheet for Recombinant Human Cathepsin D/CTSD Protein (His Tag) is available here: https://789.bio/eb/qzLGm9.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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