Recombinant Human COL9A1 Protein (Fc Tag)

Specifications

Catalog number

PKSH030873

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ubiquinone biosynthesis protein COQ7 homolog; also known as Coenzyme Q biosynthesis protein 7 homolog; Timing protein clk-1 homolog and COQ7; is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix; where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. This enzyme is responsible for the hydroxylation of 5-demethoxyubiquinone to 5-hydroxyubiquinone. Human COQ7 protein is mostly helical; and contains an alpha-helical membrane insertion. It has a potential N-glycosylation site; a phosphorylation site for protein kinase C and another for casein kinase II; and three N-myristoylation sites. COQ7 is involved in lifespan determination in ubiquinone-independent manner. It is also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator.

Synonyms

Collagen alpha-1 (IX) chain; DJ149L1.1.2; DJ149L1.1.2 ; EDM6; MED; STL4

UniProt

P20849

Accession Number

P20849-3

Expression System

HEK293 Cells

Tag

C-mFc

Sequence

Met 1-Pro328

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

59.2 kDa

Observed Molecular Weight

62-72 kDa

Species

Human