Recombinant Human LYPD3 Protein (His Tag)

Specifications

Catalog number

PKSH030987

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ly6 / PLAUR domain-containing protein 3; also known as GPI-anchored metastasis-associated protein C4.4A homolog; Matrigel-induced gene C4 protein; MIG-C4 and LYPD3; is a cell membrane protein which contains twoUPAR/Ly6 domains. Human LYPD3 contains twoUPAR/Ly6 domains. LYPD3 is expressed in placenta; skin and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues; but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression

Synonyms

C4.4A; GPI-Anchored Metastasis-Associated Protein C4.4A Homolog; LYPD3; Ly6/PLAUR Domain-Containing Protein 3; MIG-C4; Matrigel-Induced Gene C4 Protein

UniProt

B2RBR3

Accession Number

NP_055215.2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-His 286

Field of Research

Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

28.3 kDa

Species

Human