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Product details

Recombinant Human PDE9A Protein (His Tag)

Catalog number PKSH031016

Price for PKSH031016

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Size / count 100 µg

Specifications

Catalog number
PKSH031016
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
High affinity cGMP-specific 3';5'-cyclic phosphodiesterase 9A; also known as PDE9A; is a member of the cyclic nucleotide phosphodiesterase family and PDE9 subfamily. PDE9A is expressed in all tissues examined (testis; brain; small intestine; skeletal muscle; heart; lung; thymus; spleen; placenta; kidney; liver; pancreas; ovary and prostate) except blood. Highest levels of PDE9A is in brain; heart; kidney; spleen; prostate and colon. IsoformPDE9A12is found in prostate. PDE9A mRNA is widely distributed throughout the rat and mouse brain; with the highest expression observed in cerebellar Purkinje cells.PDE9A is the only cGMP-specific PDE with significant expression in the forebrain; and as such is likely to play an important role in NO-cGMP signaling. PDE9A is highly conserved between species and is widely distributed throughout the rodent brain. PDE9A is probably involved in maintenance of low cGMP levels in cells and might play an important role in a variety of brain functions involving cGMP-mediated signal transduction. PDE9A hydrolyzes the second messenger cGMP; which is a key regulator of many important physiological processes. PDE9A represents a novel drug target worthy of further study.
Synonyms
HSPDE9A2
UniProt
O76083
Accession Number
O76083-2
Expression System
E.coli
Tag
N-His
Sequence
Pro 181-Lys 506
Field of Research
Signal Transduction
Endotoxin
Please contact us for more information.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
40 kDa
Observed Molecular Weight
37 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human PDE9A Protein (His Tag)?

The catalog number for Recombinant Human PDE9A Protein (His Tag) is PKSH031016.

What sizes are available for Recombinant Human PDE9A Protein (His Tag)?

Recombinant Human PDE9A Protein (His Tag) is available in the following size(s): 100 µg.

Is Recombinant Human PDE9A Protein (His Tag) in stock?

Recombinant Human PDE9A Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human PDE9A Protein (His Tag)?

Recombinant Human PDE9A Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human PDE9A Protein (His Tag)?

Estimated delivery time for Recombinant Human PDE9A Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human PDE9A Protein (His Tag)?

The safety data sheet for Recombinant Human PDE9A Protein (His Tag) is available here: https://789.bio/eb/mTaz9G.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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