Recombinant Human CFL2/cofilin 2/ADF Protein (His Tag)

Specifications

Catalog number

PKSH031115

Size / count

50 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH-dependent manner and reduced the apparent viscosity of an actin solution, although they did not co-sediment with actin filaments at all. Cofilin2 is not expressed in vegetative cells, but is transiently induced during the aggregation stage of development, whereas cofilin 1 was predominantly expressed in vegetative cells.

Synonyms

NEM7

UniProt

Q9Y281

Accession Number

Q9Y281-1

Expression System

E.coli

Tag

N-His

Sequence

Ala 2-Leu 166

Field of Research

Signal Transduction

Endotoxin

Please contact us for more information.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

20.4 kDa

Observed Molecular Weight

21 kDa

Species

Human