Recombinant Human SAA4 Protein (GST Tag)

Specifications

Catalog number

PKSH031155

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

SAA4 is a member of the SAA family.SAA proteins are family of apolipoproteins of high density lipoprotein (HDL) . They can be separated into two distinct groups. First group (SAA1; SAA2; and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma; infection; inflammation; and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL; but this group of SAA constitutes more than 90% of all the SAA during homeostasis; and it is thought to play a role in the normal functioning of the HDL particle. SAA4 is a constitutively expressed protein which expressed only in humans and mice.It is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown; and its serum concentration has no association with those of other major apolipoproteins.

Synonyms

C-SAA; CSAA; Constitutively Expressed Serum Amyloid A Protein; SAA4; Serum Amyloid A-4 Protein

UniProt

P35542

Accession Number

P35542

Expression System

E. coli

Tag

N-GST

Sequence

Glu19-Tyr130

Field of Research

Cardiovascular; Cancer; metabolism

Endotoxin

Please contact us for more information.

Purity

> 93 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

39.8 kDa

Observed Molecular Weight

36 kDa

Formulation

Lyophilized from sterile PBS, 0.5% Triton X-100, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.

Species

Human