Recombinant Human vWF Protein (His Tag)

Specifications

Catalog number

PKSH031331-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.

Synonyms

F8VWF; VWD; Von Willebrand Factor

UniProt

P04275

Accession Number

NP_000543.2

Expression System

CHO Stable Cells

Tag

C-His

Sequence

Met 1-Lys 2813

Field of Research

Cardiovascular; Cancer; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 75 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

308.0 kDa

Observed Molecular Weight

260&350 kDa

Species

Human