Recombinant Human H1F0/Histone H1 Protein (His Tag)

Specifications

Catalog number

PKSH031355

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-terminal and C-terminal tails. These tails are moderately conserved among species, but differ among variants, suggesting a specific function for each H1 variant. Studies on the role of particular subtypes at specific developmental stages in lower eukaryotes, but also in vertebrates suggest that specific subtypes of H1 participate in particular systems of gene regulation.

Synonyms

CPN60; GROEL; H10; H1FV; HLD4; HSP60; HSP65; HSPD1; HuCHA60; SPG13

UniProt

P07305

Accession Number

P07305

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Lys 194

Field of Research

Epigenetics and nuclear signal

Endotoxin

Please contact us for more information.

Purity

> 92 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

22.4 kDa

Observed Molecular Weight

27 kDa

Species

Human