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Product details

Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag)

Catalog number PKSH031387

Price for PKSH031387

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Size / count 100 µg

Specifications

Catalog number
PKSH031387
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
MFG-E8, also known as lactadherin and MFGE8, contains 1 EGF-like domain and 2 F5/8 type C domains. It also contains a phosphatidylserine (PS) binding domain, as well as an Arginine-Glycine-Aspartic acid motif, which enables the binding to integrins. It binds PS, which is exposed on the surface of apoptotic cells. MFG-E8 is expressed in mammary epithelial cell surfaces and aortic media. Overexpression of MFG-E8 can be found in several carcinomas. MFG-E8 has an opsonization of the apoptotic cells and binding to integrins on the surface of phagocytic cells. It also mediates the engulfment of the dead cell. MFG-E8 plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. It promotes VEGF-dependent neovascularization and contributes to phagocytic removal of apoptotic cells in many tissues. It also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner.
Synonyms
BA46; EDIL1; HMFG; HsT19888; MFG-E8; MFGM; OAcGD3S; SED1; SPAG10; hP47
UniProt
Q08431
Accession Number
Q08431-1
Expression System
Baculovirus-Insect Cells
Tag
C-His
Sequence
Met 1-Cys 387
Applications
Cell culture
Field of Research
Microbiology, Cardiovascular, Developmental Biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 80 % as determined by reducing SDS-PAGE.
Bioactivity
4
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
42 kDa
Observed Molecular Weight
45 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag)?

The catalog number for Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag) is PKSH031387.

What sizes are available for Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag)?

Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag) is available in the following size(s): 100 µg.

Is Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag) in stock?

Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag)?

Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag)?

Estimated delivery time for Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag)?

The safety data sheet for Recombinant Human MFG-E8/lactadherin/MFGE8 Protein (His Tag) is available here: https://789.bio/eb/HOivP8.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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