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Product details

Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag)

Catalog number PKSH031517-01

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Price for PKSH031517-01

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Size / count 100 µg

Specifications

Catalog number
PKSH031517-01
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
NKG2D, also known as CD314, is an immune receptor which consists of two disulphide-linked type II transmembrane proteins with short intracellular proteins uncapable to transduce signals. In order to transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stimulatory signals to activate CD8 T cells. NKG2D also plays an important role in viral control. Cellular stress can induce ligands for NKG2D which results in the cell susceptible to NK cell-mediated lysis.
Synonyms
CD314; CD314 antigen; KLR; KLRK1; Killer cell lectin-like receptor subfamily K member 1; NK cell receptor D; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK recepto; killer cell lectin-like receptor subfamily K; member 1
UniProt
P26718
Accession Number
NP_031386.2
Expression System
Baculovirus-Insect Cells
Tag
N-His
Sequence
Phe78-Val216
Applications
ELISA
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
1. Immobilized human His-NKG2D (78-216) at 10 μg/ml (100 μl/well) can bind human ULBP1-Fch, The EC50 of human ULBP1-Fch is 0.04-0.08 μg/ml. 2. Immobilized human His-NKG2D (78-216) at 10 μg/ml (100 μl/well) can bind human MICB-Fch, The EC50 of human MICB-Fch is 15.9-37.1 ng/ml.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
18.4 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag)?

The catalog number for Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag) is PKSH031517.

What sizes are available for Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag)?

Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag) is available in the following size(s): 100 µg, 1 mg.

How many pack sizes does Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag) come in?

Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag) is available in 2 different pack sizes.

Is Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag) in stock?

Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag)?

Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag)?

Estimated delivery time for Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag)?

The safety data sheet for Recombinant Human NKG2D/CD314 Protein (aa 78-216, His Tag) is available here: https://789.bio/eb/8yDC8C.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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