Recombinant Human CA5A/CA-VA Protein (His Tag)

Specifications

Catalog number

PKSH031568

Size / count

50 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA5A / CA-VA is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. It is inhibited by coumarins, sulfonamide derivatives such as acetazolamide and Foscarnet (phosphonoformate trisodium salt) .

Synonyms

CA5; CA5AD; CA5D; CAV; CAVA; Carbonic Anhydrase VA; GS1-21A4.1

UniProt

P35218

Accession Number

NP_001730.1

Expression System

E.coli

Tag

C-His

Sequence

Ala 40-Ser 305

Applications

Enzyme

Field of Research

Signal Transduction; Tags & Cell Markers; metabolism

Endotoxin

Please contact us for more information.

Purity

> 96 % as determined by reducing SDS-PAGE.

Bioactivity

Measured by its esterase activity. The specific activity is > 500 pmoles/min/μg.

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

31.6 kDa

Observed Molecular Weight

33 kDa

Species

Human