Recombinant Human Carbonic Anhydrase 8/CA8 Protein (His Tag)

Specifications

Catalog number

PKSH031586-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78% of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.

Synonyms

CA-VIII; CA8; CALS; CAMRQ3; CARP; Carbonic Anhydrase VIII; Carbonic Anhydrase-Related Protein; MGC120502; MGC99509

UniProt

P35219

Accession Number

NP_004047.3

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Gln 290

Applications

Enzyme

Field of Research

Cancer

Endotoxin

Please contact us for more information.

Purity

> 94 % as determined by reducing SDS-PAGE.

Bioactivity

Measured by its esterase activity. The specific activity is > 100 pmoles/min/μg.

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

33.8 kDa

Observed Molecular Weight

37 kDa

Species

Human