Recombinant Human IL-1R9/IL1RAPL2 Protein (Fc Tag)

Specifications

Catalog number

PKSH031827-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. IL-1R9/IL1RAPL2 shows restricted expression in fetal brain and is highly homologous to IL1RAPL; which is reportedly involved in nonsyndromic X-linked mental retardation. IL-1R9/IL1RAPL2 is highly homologous to IL-1R8. Both forms have no known ligands and receptor are found in the fetal brain. IL-1R9/IL1RAPL2 may function as a negative receptor. Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins. IL-1R9/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci; and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.

Abbreviation

IL-1R9/IL1RAPL2

Synonyms

IL1R; IL-1R; TIGIRR; IL1RAPL2; IL-1R9; IL1R9; IL1RAPL-2; TIGIRR-1; IL 1 RAPL 2; IL 1 receptor accessory protein like 2; IL 1R 9; IL 1R9; IL 1RAPL 2; IL1 receptor accessory protein like 2; IL-1 receptor accessory protein-like 2; IL-1R-9; IL1RAPL 2; IL-1RAPL-2; IL-1-RAPL-2; IL1RAPL2 related protein; IL1RAPL-2-related protein; Interleukin 1 receptor 9; Interleukin 1 receptor accessory protein like 2; Interleukin-1 receptor 9; IRPL2_HUMAN; Three immunoglobulin domain containing IL1 receptor related 1; Three immunoglobulin domain-containing IL-1 receptor-related 1; TIGIRR 1; TIGIRR1; X linked interleukin 1 receptor accessory protein like 2; X-linked interleukin-1 receptor accessory protein-like 2

UniProt

Q9NP60

Accession Number

NP_059112.1

Expression System

HEK293 Cells

Tag

C-hFc

Sequence

Met 1-Glu 356

Applications

ELISA

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Measured by its ability to bind biotinylated human IL1α in functional ELISA.

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

66.0 kDa

Observed Molecular Weight

80-85 kDa

Species

Human