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Product details

Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag)

Catalog number PKSH031840-01

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Price for PKSH031840-01

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Size / count 100 µg

Specifications

Catalog number
PKSH031840-01
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra) . In clinical, it has been reported that Interleukin (IL) -1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL) -1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc) .
Abbreviation
IL-1
Synonyms
IL1F; IL-1F; pro IL1F; IL-1; IL1-BETA; IL1F2; IL1 beta; IL1B; catabolin; IL-1B; pro Catabolin; pro IL1B; pro IL1F2; pro leukocytic endogenous mediator; pro leukocytic pyrogen; pro lymphocyte activating factor; pro mononuclear cell factor; IL-1F2; IL 1B; IL-1 beta
UniProt
P01584
Accession Number
NP_000567.1
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Ser 269 (Glu6Lys)
Applications
ELISA
Field of Research
Cardiovascular; immunology; metabolism
Endotoxin
Please contact us for more information.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Immobilized human IL1B at 10 μg/mL (100 μl/well) can bind human IL1R1.The EC50 of human IL1R1 is 0.198 μg/mL.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
32.3 kDa
Observed Molecular Weight
34 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag)?

The catalog number for Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag) is PKSH031840.

What sizes are available for Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag)?

Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag) is available in the following size(s): 100 µg, 1 mg.

How many pack sizes does Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag) come in?

Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag) is available in 2 different pack sizes.

Is Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag) in stock?

Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag)?

Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag)?

Estimated delivery time for Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag)?

The safety data sheet for Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag) is available here: https://789.bio/eb/fvTCWD.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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