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Product details

Recombinant Human VEGF-A/VEGF121 Protein (His Tag)

Catalog number PKSH031983-01

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Price for PKSH031983-01

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Size / count 10 µg

Specifications

Catalog number
PKSH031983-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Human VEGF121; also known as Vascular endothelial growth factor A; VEGFA; Vascular permeability factor; VPF and VEGF; is a homodimeric; heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF) /vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects; including mediating increased vascular permeability; inducing angiogenesis; vasculogenesis; permeabilization of blood vessels and endothelial cell growth; increasing microvascular permeability; promoting cell migration and inhibiting apoptosis. Alternatively spliced transcript variants of VEGF-A encod either secreted or cell-associated isoforms. The lymphangiogenesis may be promoted by upregulation of VEGF121; which may in turn act in part via induction of VEGF-C. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors; heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways; does not activate angiogenesis and inhibits tumor growth.
Abbreviation
VEGF-A; VEGF121
Synonyms
VEGF; VEGF-A; VEGFA; VPF; Vascular endothelial growth factor A; Vascular permeability factor
UniProt
P15692
Accession Number
P15692-9
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala27-Arg147
Field of Research
Signal Transduction; Cardiovascular; Cancer; Developmental Biology; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
15.1 kDa
Observed Molecular Weight
16-18 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human VEGF-A/VEGF121 Protein (His Tag)?

The catalog number for Recombinant Human VEGF-A/VEGF121 Protein (His Tag) is PKSH031983.

What sizes are available for Recombinant Human VEGF-A/VEGF121 Protein (His Tag)?

Recombinant Human VEGF-A/VEGF121 Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human VEGF-A/VEGF121 Protein (His Tag) come in?

Recombinant Human VEGF-A/VEGF121 Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human VEGF-A/VEGF121 Protein (His Tag) in stock?

Recombinant Human VEGF-A/VEGF121 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human VEGF-A/VEGF121 Protein (His Tag)?

Recombinant Human VEGF-A/VEGF121 Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human VEGF-A/VEGF121 Protein (His Tag)?

Estimated delivery time for Recombinant Human VEGF-A/VEGF121 Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human VEGF-A/VEGF121 Protein (His Tag)?

The safety data sheet for Recombinant Human VEGF-A/VEGF121 Protein (His Tag) is available here: https://789.bio/eb/yfHCm9.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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