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Product details

Recombinant Human IL-12 p40/IL-12B Protein

Catalog number PKSH032004-01

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Price for PKSH032004-01

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Size / count 10 µg

Specifications

Catalog number
PKSH032004-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.
Abbreviation
IL-12 p40; IL-12B
Synonyms
IL-12/IL-23 p; IL-12 subunit p; NK cell stimulatory factor chain; NK cell Stimulating Factor Chain; CLMF p; IMD; IL12B; CLMF; CLMF2; IL-12B; IMD28; IMD29; NKSF; NKSF2; Cytotoxic lymphocyte maturation factor 40 kDa subunit; Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40) ; IL-12/IL-23 p40; NK cell Stimulating Factor Chain 2; p40; Interleukin-12 subunit beta; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; IL 12B; IL12 p40; Interleukin 12 beta chain; Interleukin 12 p40
UniProt
P29460
Accession Number
P29460
Expression System
HEK293 Cells
Tag
None
Sequence
Ile23-Ser328
Field of Research
Microbiology; Cancer; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
34.6 kDa
Observed Molecular Weight
40-47 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human IL-12 p40/IL-12B Protein?

The catalog number for Recombinant Human IL-12 p40/IL-12B Protein is PKSH032004.

What sizes are available for Recombinant Human IL-12 p40/IL-12B Protein?

Recombinant Human IL-12 p40/IL-12B Protein is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human IL-12 p40/IL-12B Protein come in?

Recombinant Human IL-12 p40/IL-12B Protein is available in 2 different pack sizes.

Is Recombinant Human IL-12 p40/IL-12B Protein in stock?

Recombinant Human IL-12 p40/IL-12B Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human IL-12 p40/IL-12B Protein?

Recombinant Human IL-12 p40/IL-12B Protein is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human IL-12 p40/IL-12B Protein?

Estimated delivery time for Recombinant Human IL-12 p40/IL-12B Protein is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human IL-12 p40/IL-12B Protein?

The safety data sheet for Recombinant Human IL-12 p40/IL-12B Protein is available here: https://789.bio/eb/KuLC0C.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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