Recombinant Human EphA4 Protein

Specifications

Catalog number

PKSH032008-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ephrin type-A receptor 4 (EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain; 2 fibronectin type-III domains; 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events; particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Abbreviation

EphA4

Synonyms

EK8; EPH-like kinase 8; EPHA4; Ephrin type-A receptor 4; HEK8; SEK; TYRO1; Tyrosine-protein kinase TYRO1; Tyrosine-protein kinase receptor SEK; hEK8

UniProt

P54764

Accession Number

P54764

Expression System

HEK293 Cells

Tag

None

Sequence

Val20-Thr547

Field of Research

Signal Transduction; Cardiovascular; Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

59.2 kDa

Observed Molecular Weight

60-80 kDa

Species

Human