Recombinant Human BDH2 Protein (His Tag)

Specifications

Catalog number

PKSH032020-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of 3-Hydroxybutyrate Dehydrogenase Type 2 make it suitable to conbert high levels of circulating 3-hydroxybutyrate into acetoacetate.

Abbreviation

BDH2

Synonyms

3-Hydroxybutyrate Dehydrogenase Type 2; BDH2; DHRS6; Dehydrogenase/Reductase SDR Family Member 6; Oxidoreductase UCPA; R-Beta-Hydroxybutyrate Dehydrogenase

UniProt

Q9BUT1

Accession Number

AAH01953.1

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Leu245

Field of Research

Signal Transduction; Cell biology; Cardiovascular; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

28.9 kDa

Observed Molecular Weight

30 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.

Species

Human