Recombinant Human APBA3 Protein (His Tag)

Specifications

Catalog number

PKSH032064-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the β-amyloid precursor protein (APP) and hence formation of β-APP.

Abbreviation

APBA3

Synonyms

APBA3; Adapter protein X11Gamma; Amyloid Beta A4 Precursor Protein-Binding Family A Member 3; MINT3; Mint-3; Neuron-Specific X11L2 Protein; Neuronal Munc18-1-Interacting Protein 3; X11L2

UniProt

O96018

Accession Number

O96018

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Leu138

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

15.5 kDa

Observed Molecular Weight

20 kDa

Species

Human