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Product details

Recombinant Human ACE2 Protein (His Tag)

Catalog number PKSH032068-01

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Price for PKSH032068-01

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Size / count 10 µg

Specifications

Catalog number
PKSH032068-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Abbreviation
ACE2
Synonyms
ACE-Related Carboxypeptidase; ACE2; ACEH; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Homolog; Metalloprotease MPROT15
UniProt
Q9BYF1
Accession Number
Q9BYF1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln18-Ser740
Applications
BLI
Field of Research
Cell biology; Cardiovascular
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Loaded 2019-nCoV S Protein RBD-mFc on AMC Biosensor, can bind Human ACE-2-His with an affinity constant of 2.06 nM as determined in BLI assay.
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
84.6 kDa
Observed Molecular Weight
103 kDa
Formulation
2
Citation 01
https://www.mdpi.com/1844936
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human ACE2 Protein (His Tag)?

The catalog number for Recombinant Human ACE2 Protein (His Tag) is PKSH032068.

What sizes are available for Recombinant Human ACE2 Protein (His Tag)?

Recombinant Human ACE2 Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human ACE2 Protein (His Tag) come in?

Recombinant Human ACE2 Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human ACE2 Protein (His Tag) in stock?

Recombinant Human ACE2 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human ACE2 Protein (His Tag)?

Recombinant Human ACE2 Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human ACE2 Protein (His Tag)?

Estimated delivery time for Recombinant Human ACE2 Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human ACE2 Protein (His Tag)?

The safety data sheet for Recombinant Human ACE2 Protein (His Tag) is available here: https://789.bio/eb/qDSGa5.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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