Recombinant Human Angiotensinogen/AGT Protein (His Tag)

Specifications

Catalog number

PKSH032069-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Abbreviation

Angiotensinogen; AGT

Synonyms

AGT and SERPINA8; ANHU; Angiotensinogen; Serpin A8

UniProt

P01019

Accession Number

AAH11519.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Asp34-Ala485

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

50.8 kDa

Observed Molecular Weight

55-75 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Species

Human