Recombinant Human ASB13 Protein (His Tag)

Specifications

Catalog number

PKSH032070-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ankyrin repeat and SOCS box protein 13 (ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Abbreviation

ASB13

Synonyms

ASB13; Ankyrin repeat and SOCS box protein 13

UniProt

Q8WXK3

Accession Number

Q8WXK3

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Asn278

Field of Research

Cell biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

31.4 kDa

Observed Molecular Weight

28 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, 4M Urea, pH 7.4.

Species

Human