Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag)

Specifications

Catalog number

PKSH032084-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.

Abbreviation

Apolipoprotein C-II; APOC2

Synonyms

APC2 and APOC2; Apolipoprotein C-II; Apolipoprotein C2

UniProt

P02655

Accession Number

AAP35354.1

Expression System

E.coli

Tag

C-His

Sequence

Thr23-Glu101

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

10.0 kDa

Observed Molecular Weight

14 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4.

Species

Human