Recombinant Human Apolipoprotein H/ApoH Protein (His Tag)

Specifications

Catalog number

PKSH032087-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Apolipoprotein H (ApoH) is a 50 kDa variably glycosylated member of the complement control superfamily of proteins. Human ApoH is a major phospholipid binding protein and an important component to measure in the assessment of anti-phospholipid syndrome. Hepatocyte-derived ApoH binds to negatively charged phospholipids . It circulates as a component of lipoprotein particles and as a lipid-free serum protein. Human ApoH is also more specific than anti-cardiolipin antibodies and its presence correlates better with thrombotic risk. Mature human ApoH shares 76% and 82% aa sequence identity with mouse and rat ApoH.

Abbreviation

Apolipoprotein H; ApoH

Synonyms

APC inhibitor; APOH; Activated Protein C-Binding Protein; Anticardiolipin Cofactor; Apo-H; Apolipoprotein H; B2G1; B2GP1; B2GPIBeta (2) GPI; BG; Beta-2-Glycoprotein 1; Beta-2-Glycoprotein I

UniProt

P02749

Accession Number

P02749

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gly20-Ser345

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

37.3 kDa

Observed Molecular Weight

45-70 kDa

Species

Human