Recombinant Human BPI/CAP57 Protein (His Tag)

Specifications

Catalog number

PKSH032108-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Bactericidal permeability-increasing protein (BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, and this activity is inhibited by LPS from P.aeruginosa.

Abbreviation

BPI; CAP57

Synonyms

BPI; Bactericidal permeability-increasing protein; CAP57

UniProt

P17213

Accession Number

AAH40955.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Val32-Lys487

Field of Research

Microbiology; Cardiovascular; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

51.6 kDa

Observed Molecular Weight

50-60 kDa

Species

Human