Recombinant Human BLVRA Protein (His Tag)

Specifications

Catalog number

PKSH032118-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Human Biliverdin reductase A (BLVRA) is belonged to the Gfo/Idh/MocA family and Biliverdin reductase subfamily. BLVRA is an enzyme that in humans is encoded by the BLVRA gene. BLVRA plays an important role in reducing the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. BLVRA acts on biliverdin by reducing its double-bond between the pyrrole rings into a single-bond. It accomplishes this using NADPH + H+ as an electron donor, forming bilirubin and NADP+ as products.

Abbreviation

BLVRA

Synonyms

BLVR; BLVRA; BVR; BVR A; Biliverdin reductase A; Biliverdin-IX alpha-reductase

UniProt

P53004

Accession Number

P53004

Expression System

E.coli

Tag

C-His

Sequence

Glu6-Ser294

Field of Research

Signal Transduction; Cell biology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

33.8 kDa

Observed Molecular Weight

35-45 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 50% Glycerol, pH 8.0.

Species

Human