Recombinant Human Cadherin-17/CDH17 Protein (His Tag)

Specifications

Catalog number

PKSH032139-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role in the morphological organization of liver and intestine and involved in intestinal peptide transport.

Abbreviation

Cadherin-17; CDH17

Synonyms

CDH16; CDH17; Cadherin-17; HPT-1; HPT1; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; Liver-Intestine Cadherin

UniProt

Q12864

Accession Number

AAI13465.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln23-Met787

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

86.0 kDa

Observed Molecular Weight

110-130 kDa

Species

Human