Recombinant Human Carboxypeptidase M/CPM Protein (His Tag)

Specifications

Catalog number

PKSH032174-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Carboxypeptidase M (CPM) specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. Carboxypeptidase exert roles in the physiological processes of blood coagulation/fibrinolysis, inflammation, food digestion and pro-hormone and neuropeptide processing. CPM is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins. It is widely distributed in a variety of tissues and cells. CPM is involved in peptide metabolism on both the cell surface and in extracellular fluids. CPM functions not only as a protease but also as a binding partner in cell-surface protein-protein interactions.

Abbreviation

Carboxypeptidase M; CPM

Synonyms

CPM ; Carboxypeptidase M

UniProt

P14384

Accession Number

P14384

Expression System

HEK293 Cells

Tag

C-His

Sequence

Leu18-His422

Field of Research

Signal Transduction; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

47.3 kDa

Observed Molecular Weight

55 kDa

Formulation

2

Species

Human