Recombinant Human Cathepsin L2/CTSL2 Protein (His Tag)

Specifications

Catalog number

PKSH032183-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cathepsin L2 belongs to the Peptidase C1 family. Cathepsin L2 can be autocatalytically convertedto the mature form as a proenzyme in lysosomes at pH=7.0. Cathepsin L2 cannot be expressed in normal mammary gland, colon and peritumoral tissue, but it can be expressed in breast carcinomas and colorectal tissues. These suggeats Cathepsin L2 may play a role in tumor processes. Cathepsin L2 is specifically expressed in the testis, thymus, and corneal epithelium.

Abbreviation

Cathepsin L2; CTSL2

Synonyms

CATL2; CTSL2; CTSU; CTSV; Cathepsin L2; Cathepsin U; Cathepsin V

UniProt

O60911

Accession Number

O60911

Expression System

HEK293 Cells

Tag

C-His

Sequence

Val18-Val334

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

36.7 kDa

Observed Molecular Weight

33-43 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween 80, pH5.5.

Species

Human