Recombinant Human CCL18 Protein (His Tag)

Specifications

Catalog number

PKSH032189-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 is a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 may be involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.

Abbreviation

CCL18

Synonyms

AMAC-1; Alternative Macrophage Activation-Associated CC Chemokine 1; C-C Motif Chemokine 18; CC Chemokine PARC; DC-CK1; Dendritic Cell Chemokine 1; MIP-4; Macrophage Inflammatory Protein 4; Pulmonary and Activation-Regulated Chemokine; Small-Inducible Cytokine A18

UniProt

P55774

Accession Number

P55774

Expression System

E.coli

Tag

N-His

Sequence

Ala21-Ala89

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

10.1 kDa

Observed Molecular Weight

13 kDa

Species

Human