Recombinant Human CD27/TNFRSF7 Protein (Fc & His Tag)

Specifications

Catalog number

PKSH032210-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD27 antigen is also known as CD27L receptor; T-cell activation antigen CD27; Tumor necrosis factor receptor superfamily member 7; T14 and TNFRSF7. In humans; it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70; and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.

Abbreviation

CD27; TNFRSF7

Synonyms

S152; S152. LPFS2; S152.LPFS2; T14; TNFRSF7; Tp55

UniProt

P26842

Accession Number

P26842

Expression System

HEK293 Cells

Tag

C-Fc-His

Sequence

Thr 21-Ile192

Field of Research

Cancer; immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

47.2 kDa

Observed Molecular Weight

60 kDa

Species

Human